In-vitro fertilisation (IVF), the advanced reproductive technology, combines sperm and an egg outside the body in a laboratory setting. This procedure has helped millions of couples conceive a child worldwide, yet, not all IVF treatments are booming, as many factors can impact the success rate. One of these factors is the quality of the DNA contained in the sperms. DNA fragmentation testing is an effective method to measure the DNA’s quality, increasing the odds of a successful IVF procedure.

We prioritise patient education ahead of anything else, so we’d like to take some time to discuss DNA fragmentation testing, what it entails and why it could benefit anyone considering the best IVF treatment.

What Is DNA Fragmentation Testing?

If you’re considering IVF treatment, one crucial step you can take beforehand is to have your DNA fragmentation tested at Benison IVF and Health Care Clinic. It is a type of testing designed to determine the quality of your DNA. Knowing such facts allows you to become more conscious of your fertility, and we can help you select suitable treatments in your best interests.

With DNA fragmentation testing, we assess how much of your sperm is composed of healthy, active sperm cells and how much contains unhealthy or inactive cells. To foresee complications that might develop later, we consider additional parameters – for instance, the reliability of the DNA and its overall shape.
At Benison IVF & Health Care Clinic, our DNA fragmentation testing services are second to none – we use cutting-edge technology and state-of-the-art laboratory techniques for accurate and reliable results. So if you’re considering IVF, it’s worth taking advantage of this essential test before beginning treatment.

How Does DNA Fragmentation Affect Fertility?

Research has demonstrated that having significantly elevated DNA fragmentation levels in one’s sperm may greatly reduce the likelihood of successful conception and resulting pregnancy. Studies have revealed that males with abundant levels of DNA fragmentation were more vulnerable to infertility than those with lower fragmentation levels. Additionally, a further survey suggested that couples participating in IVF treatment were less likely to achieve conception if the male partner had considerable DNA fragmentation levels.

Why Is DNA Fragmentation Testing Important?

DNA fragmentation testing is an essential factor for evaluating the quality of sperms in IVF procedures. Here are some of the critical benefits of DNA fragmentation testing:

• Increased Success Rate: DNA fragmentation testing can help improve the success rate of IVF procedures by identifying potential issues with the quality of sperm. By addressing these issues before the procedure, doctors can increase the chances of successful fertilisation and implantation.

• Reduced Miscarriage Rate: DNA fragmentation testing can also help reduce the risk of miscarriage by identifying potential issues with DNA quality in the sperm. This information can help doctors provide appropriate treatment and care to minimise the risk of a miscarriage.

• Cost-Effective: DNA fragmentation testing is a cost-effective way to evaluate the quality of sperms. It can provide valuable information to doctors and patients before the IVF procedure. By identifying potential issues early on, doctors can avoid costly and time-consuming processes that may not be successful.

Who Should Consider DNA Fragmentation Testing?

DNA fragmentation testing has been available in the medical industry for some time. But who should consider getting this type of testing done? Take a look at the categories of people who must consider going for this test:

• Couples with unexplained infertility: Experiencing infertility issues with no apparent cause? Consider undergoing DNA Fragmentation testing to help you identify any potential problems. This testing can help you determine if a specific sperm abnormality is causing your inability to conceive.

• Recurring IVF/Implantation failure: If you have tried conceiving through IVF procedure multiple times, you must consider opting for DNA Fragmentation testing.

• Recurrent Pregnancy Loss: We highly recommend DNA Fragmentation testing for those who have experienced repeated cases of miscarriage.

Speak to our doctors and know if you should get tested. Doing so could significantly improve your chances of conceiving successfully and minimise any risks to fertility treatment outcomes.

How Is The Test Conducted At Benison IVF And  Health Care Clinic?

Benison IVF & Health Care Clinic stands out from its competitors as it offers DNA Fragmentation Testing, which can be invaluable in identifying any potential obstacles to successful conception. See below how this test works:

Testing process: At Benison IVF & Health Care Clinic, appropriate samples are incubated for three hours and tested using any of the four different tests each: terminal deoxynucleotidyl transferase (TdT) assay, Comet Assay or single-cell gel electrophoresis (SCGE), Sperm Chromatin Structure Assay (SCSA) and Acridine Orange Staining (AOS). Each test measures different components present in the cell, such as nuclear damage, chromosomal abnormalities and morphology. These tests allow us to provide our clients with detailed information about the fertilising capability of their sperm. Additionally, the results are used to refine recommendations for treatment options if needed. Using DNA fragmentation testing at Benison IVF & Health Care Clinic, couples can better understand their fertility status and develop a more effective plan for conceiving a baby.

Benefits Of DNA Fragmentation Testing

DNA fragmentation testing provides patients with valuable information about their embryos. This kind of testing provides a better visualisation of possible success rates and can help understand how to utilise the production process best.

Sperm DNA Fragmentation testing is an additional investigation that can be added to your treatment if your IVF doctor at Benison IVF & Health Care Clinic finds it necessary to be done.

Why Choose Benison IVF?

At Benison IVF Centre, DNA fragmentation testing is an add-on tool used to evaluate the quality of sperm cells before initiating fertility treatment in selective cases. This specialised test provides clinicians with a comprehensive analysis of the sperm DNA, enabling them to make individualised treatment decisions that optimise success rates.

By utilising this advanced technology, the Benison IVF and Health Care Clinic doctors can make more informed decisions, leading to the best possible outcome for their patients. This cutting-edge approach to fertility care, coupled with a team of experienced fertility specialists, places Benison IVF Health Care Clinic at the forefront of the field. The clinic’s unwavering commitment to providing patients with the highest quality of care ensures that every individual receives personalised and compassionate attention throughout their fertility journey.

Frequently Asked Questions

Q.1 What is the role of DNA fragmentation testing in IVF procedures?

DNA fragmentation testing can play a role in IVF procedures by identifying sperm.

Q.2 Can lifestyle adjustments and medical treatments improve the DNA fragmentation levels in sperm?

Lifestyle adjustments and medical treatments can help improve the DNA fragmentation levels in sperm. Quitting smoking, reducing alcohol consumption, and avoiding exposure to toxins can all help improve sperm quality. Medical treatments such as antioxidant therapy or varicocele repair may also be recommended to improve sperm DNA quality.

Q.3 How can DNA fragmentation testing help reduce the risk of miscarriage?

It can reduce the risk of miscarriages by identifying poor DNA integrity as a cause of infertility and receiving appropriate treatment for the same.

Q.4 Who should consider DNA fragmentation testing?

Couples struggling with infertility, recurrent miscarriages, or unexplained infertility should think about getting tested for DNA fragmentation. Men with a history of smoking, exposure to toxins, or any other potential risk factors of DNA damage should also benefit from such a test.